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Rapamycin for Dogs — FAQs
Here are a few of the most commonly asked questions about rapamycin for dogs and its purchase. We’ll be adding to these over the next few weeks, but please reach out to me with other questions as they pop up. Thanks, Dr. Kevin
How can I buy rapamycin for dogs?
There are two ways to purchase rapamycin for your dog:
- with a prescription from your veterinarian
- with an in person exam/consult with me on the Central Coast of California. The weather’s great– come on out!!
If your pet has cancer or progressive cardiac disease, please reach out to me below. I have a special interest in helping these pets out.
What is the rapamycin dosage for dogs?
Our dosing is based on the Kaeberlein study on rapamycin for dogs at University of Washington,, and translates into 1 mg per 20-22 lbs of your pet’s weight given 3x weekly with food. Thus, 12 capsules will provide one month’s worth of benefits to your pet.
How do I know the quality of your rapamycin for dogs?
That is a GREAT question, given the variety of scams floating around on the web. And here is the answer.
We independently test every batch of rapamycin we get before it is encapsulated. Here is the latest test result for our rapamycin, showing that it is 99.944% pure.
Once the purity has been established, I hand deliver the rapamycin to a family pharmacy that is 4 blocks away from my home, and whom I have trusted with my prescriptions for over ten years.
That’s how I can guarantee our rapamycin for dogs.
What does science tell us about rapamycin’s health benefits?
The studies available to date have taken place mostly in small mammals, with the notable exception of the Kaeberlein study mentioned above.
These studies have demonstrated that patients on rapamycin have…
- 9-30% longer lifespan
- reduced cancer incidence
- improved immune function
- improved stem cell function
- reduced joint inflammation
- improved cardiac function, most notably in DOGS with pre-existing disease
- reduced periodontal disease
- better hearing in old individuals
Why should I give my dog rapamycin?
Here are the most common reasons caring pet owners begin their dog on rapamycin…
- science suggests that it may increase lifespan
- to help cardiac disease
- to reduce pain and inflammation
- to fight cancer
Here are the benefits reported to us by parents of pets on our rapamycin:
- Subjectively happier pets
- Better spinal function — less wobbliness
- Better cardiac function, according to their veterinarian
- Increased ability to exercise
- In two cases of dogs with chronic kidney disease, we have seen improvement in blood markers.
- In two cases of oral melanoma, we have seen tumor size plateau or shrink.
About 20% of our patients have terminal cancer, and so we measure success in these patients as maintaining their quality of life.
Some pets show no outward change whatsoever on rapamycin. I don’t believe that this means rapamycin is not benefitting these pets and their metabolic function — I believe in the science behind rapamycin, rather than the symptoms any pet exhibits.
I take rapamycin from the same bottle I prescribe for pets. On those days, I don’t feel any different myself — no jumping over tall buildings for me. But I trust the science.
How safe is rapamycin for my dog?
Listen, every drug in the world has potential side effects, and rapamycin is no different. If you want a 100% guarantee on something, you better not take a drug… any drug. Or leave the house, for that matter.
The use of rapamycin for longevity purposes, human or pet, is CLEARLY an off-label use. You need to do your own research and decide whether the potential benefits outweigh the risks for your pet.
At high doses, its primary use in humans is as an immune suppressant. At those doses, it is known to also create changes in blood cell counts, lipid and sugar levels. Here is a link to the adverse effects summary of rapamycin on Drugs.com.
A better question is the side effects that occur in DOGS at the doses we recommend, which are based upon the Kaeberlein study from University of Washington.
At these doses, Dr. Kaeberlein’s group reported NO adverse effects during the study. Likewise, we have seen NO adverse effects in over 130 dogs that we have treated with rapamycin.
I take rapamycin from the same bottle that I use for my patients, and give it to my own dogs. Can’t say much more than that.
Are there dogs who should not take rapamycin?
We have seen no adverse effects in ANY patient to date, including those patients with kidney disease or cancer.
Having said that, there are dog patients with whom I’d be a little cautious. This includes dogs with …
- Pre-existing liver disease
- Pre-existing diabetes
At the doses we prescribe, rapamycin is generally thought to have an immune stimulant rather than immune suppressive activity. However, it is logical to avoid rapamycin if your dog has a chronic bone infection or chronic fungal diseases prevalent in certain geographic areas.
If you have questions about your dog and a particular health issue, please reach out to me and we’ll do the research together.
How do I know that rapamycin is working for my pet?
The bad news is that at this time we have no biomarker to measure either rapamycin benefits or longevity, either in pets or humans. ALL OF US hope that such a biomarker will be identified… but that may be decades away.
Listen, I take the same rapamycin capsules I send your way, and give them to my dogs as well. I don’t feel any different when I take the rapa, but I am a believer in the SCIENCE instead of the symptoms.
Is there a chance that a decade from now we will learn that rapamycin is of no benefit to our pets? Yes, there is that chance.
However, that chance would mean that our dogs are DIFFERENT FROM EVERY OTHER SPECIES studied to date… in which the benefits have been proven.
Here are the bottom lines for me:
- Rapamycin has been proven safe in pets, both in studies and in our own patients.
- Science shows a multitude of health/longevity benefits to rapamycin in every species studied to date, and I don’t think our dogs will prove different.
- The proof of these benefits is likely long years to decades away, which does not help the pets that we love so much.
MY VOTE? For rapamycin.
What else can I do to help my pet live longer and happier?
In addition to the use of rapamycin, there are two clear paths to a longer life for our dogs:
- MINIMIZING THEIR WEIGHT
- MINIMIZING INFLAMMATION
Of course, your dog might not like the first suggestion 🙂 But in every species studied to date, one of the most powerful ways to extend life is…. caloric restriction.
The other way to extend life is to minimize aging due to inflammation, or “inflamm-aging”. One EASY way to do that is with our supplement LONGEVITY PLUS, which contains curcumin, boswellia, and ashwagandha.
The big three in inflammatory diseases for your dog are…
- Dental disease
… and we can help you solve them, too.
Can we ship rapamycin for dogs outside the US?
Yes, we can.
There is an additional cost of $45 USD for shipping out side the US. We ship internationally via USPS Priority Mail, and those shipments can be tracked.
In my experience, about 80% of the time we don’t run into any problems with Customs. However, there have been times when the shipment has been flagged and returned by different countries’ customs service, and we cannot return your payment under those circumstances.
Here is a list of countries to whom we have successfully shipped rapamycin for dogs:
- New Zealand
…. BUT NOT POLAND.
Have other questions about rapamycin for your dog?
More Rapamycin for Dogs — FAQs coming soon….
More Rapamycin for Dogs — FAQs coming soon….